Polyhexamethylene Biguanide Hydrochloride, short for PHMB, CAS 32289-58-0, is a cationic polymeric guanidine disinfectant with broad-spectrum antimicrobial performance. The guanidine group carries strong positive charge, which can adsorb negatively charged bacteria, fungi, algae, destroy cell membrane structure, block microbial respiration, and rapidly kill microorganisms without drug resistance. PHMB features low toxicity, mild irritation, long-lasting antibacterial effect, stable chemical property, no volatility, high temperature resistance. It has two mainstream forms: 20% transparent aqueous solution for bulk industrial use and 98% high-purity crystal powder for cosmetic & medical formulation.
Main Application Fields Water Treatment Industry Cooling tower, circulating water, swimming pool disinfection, algaecide; industrial wastewater sterilization, sludge flocculation, remove suspended solids & microorganisms. Low dosage 1--5ppm, no corrosion to pipeline. Cosmetic & Personal Care Preservative Approved preservative for lotion, cream, hand sanitizer, contact lens care liquid, mask essence; inhibit gram-positive/negative bacteria, yeast, mold, mild skin irritation, replace parabens. Medical & Healthcare Surgical wound disinfection, antibacterial gauze, dressing, medical instrument surface sanitizer; low stimulation allows direct contact damaged skin, relieve inflammation. Textile Antibacterial Finishing Antibacterial finishing for towel, underwear, bedding, baby clothes, medical textile; durable antibacterial layer after finishing, anti-odor, anti-mite. Aquaculture Breeding Fish & shrimp pond water disinfection, reduce red body, rotten gill, algae overgrowth; reduce ammonia nitrogen, balance water ecology, safe for aquatic organisms. Daily Cleaning & Household Disinfectant Hand soap, laundry detergent, multi-surface cleaner, floor disinfectant raw material.